- Pds1 / Esp1 Mutants
- pds1∆
- pds1∆ in nocodazole
- bub2∆ pds1∆ in nocodazole
- mad2∆ pds1∆ in nocodazole
- cdc20∆ pds1∆
- cdc20∆ pds1∆ clb5∆
- CLB5-db∆ pds1∆
- CLB5-db∆ pds1∆ cdc20∆
- CLB1 clb2∆ pds1∆
- esp1-ts
- GAL-PDS1-db∆ esp1-ts
- GAL-PDS1-db∆
- PDS1-db∆
- GAL-ESP1 cdc20-ts
bub2∆ pds1∆ in nocodazole
debug: ,
test user =
test db =
Simulation:
Change of parameters: kbub2=0, ks1pds"=ks2pds"=0, ksspn=0, init BUB2=0.
Arrest: Mitotic exit at t=147.9 min.
Experiments:
Alexandru, G., Zachariae, W., Schleiffer, A. and Nasmyth, K. (1999). Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage. EMBO J. 18:2707-2721.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Fig. 6B, these mutants are not blocked in nococazole, they are able to exit from mitosis.
Comments:
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